When is the best time to sell crypto Crypto investing can both be an exciting and wild experience at the same time. It can cause you a lot of happiness or stress depending on the state of the market. Also, the ultimate goal of every crypto investor is to eventually sell and earn a profit. Similar to investing in stocks, a good rule of thumb to stick by is to buy and hold your assets for at least the long-term duration which usually takes 5-10 years.